For the occasional removal of artifacts or enchantments, I will give preference to an Acidic Slime over a Nature's Claim
While its technically possible to give a player poison counters directly (Caress of Phyrexia comes to mind), the most popular poison counters strategy involves running a bunch of infect or toxic creatures
This, partnered with the Sabrina Trainer card, will have the player questioning their next move
Jeskai Cycling refers to Timeless Wisdom and Gavi, Nest Warden
Before shuffling your deck to become your library, you may reveal one card from outside the game to be your companion if your starting deck meets the requirements of the companion ability
Similarly, if the Mayor is blocked by a 2/2 with first strike, he will die before your other 2 humans get to deal damage in the second damage step, where they will just be 2/2s again