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Gandotinib (LY2784544) Griffin CCT129202 is an ATP-competitive pan-Aurora

SKU: 84123189598

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Description

CCT129202 is an ATP-competitive pan-Aurora inhibitor for Aurora A

Ginkgolide A is an extract from in Ginkgo biloba and a g-aminobutyric acid (GABA) antagonist with a Ki of 14

Also a DNA synthesis inhibitor in vascular smooth muscle cells

Amiloride is a selective T-type calcium channel blocker

It shows 4- and 11-fold greater selectivity against Plk2 and Plk3

Gandotinib (LY2784544) Griffin CCT129202 is an ATP-competitive pan-AuroraGandotinib (LY2784544) is a potent JAK2 inhibitor with IC50 of 3 nM, effective in JAK2V617F, 8 and 20 fold selective versus JAK1 and JAK3. Phase 2.

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