Human FcRn GST Amount:250 µg A homologue of the TNF

A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function

mast cells

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Najakshin AM

Loetscher H

Human FcRn GST Amount:250 µg A homologue of the TNFHuman neonatal Fc receptor (FcRn) was named for its role in transferring IgG molecules across placenta to the fetus. Structurally, it is distinct from the classical IgG receptors for its similarity to the MHC class I instead of the Ig superfamily (IgSF) molecules. Binding of FcRn to IgG protects the latter from being proteolytically attacked by the endocytic lysosomal enzymes. The preservation of the antibody molecules by FcRn is central to the