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TNF promotes the inflammatory responses that often lead to autoimmune disorders such as rheumatoid arthritis
Biochemical properties of the 75-kDa tumor necrosis factor receptor
is a member of the TNFR superfamily and plays important roles in bone physiology as well as in regulation of the interactions between dendritic cells and T lymphocytes
19(9):576-91
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Human TNFR2 Mouse IgG2a Wildtype Fc Amount:10 mg TNF promotes the inflammatory responsesTNFR2 is a single pass type I membrane protein and the member of TNFR superfamily containing 4 cysteine rich domains (CRD) repeats. In addition to the full length membrane anchored form, soluble TNFR2 can be generated via two distinct mechanisms: (1) shedding via proteolytic processing of the full membrane anchored from, and (2) translation from an alternatively spliced message encoding the extracellular domains of TNFR2. Interacting protein(s): TNF
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