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Tideglusib Funnel 11-fold greater selectivity for B-Raf

SKU: 17780352044

4.2
USD485.00 USD516.00

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Description

11-fold greater selectivity for B-Raf over c-Raf

ZM 447439 is a selective and ATP-competitive inhibitor for Aurora A and Aurora B with IC50 of 110 nM and 130 nM

5-fold less potent to Flt3

Corning Thermowell GOLD 0

which considerably expands the MYA 4Y PLUS microbalance functionality

Tideglusib Funnel 11-fold greater selectivity for B-RafTideglusib is an irreversible, non ATP competitive GSK 3? inhibitor with IC50 of 60 nM in a cell free assay; fails to inhibit kinases with a Cys homologous to Cys 199 located in the active site. Phase 2.

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