Besides under my own control, I once saw this card blow out a player as it was flashed in via an emergency [casthaven]Collected Company[/casthaven] in response to [casthaven]Damnation[/casthaven] as a way to prevent most of the profit for a soon-to-ultimate [casthaven]Liliana Vess[/casthaven]
If you dont have lands or artifacts to give yourself mana or magical energy, other than in rare instances, you cant play other cards from your hand
The force of a blizzard
Vito, Thorn of the Dusk Rose Exquisite Blood plus Vito, Thorn of the Dusk Rose is the name of the game for life-based combo decks
"I'm going to play a land as my 61st card so that I have the perfect ratio of lands to spells." While your land-to-spell ratio may be more mathematically correct, you are still reducing the odds of drawing your best cards by doing this
While the additional Kicker can only be paid while casting a spell, Power-up can be paid when you cast the creature (at a reduced cost) or later on for more mana