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The inhibiting SHP2 activity of SHP099 is through an allosteric mechanism
Product Name Pomalidomide-C3-amine HCl Synonyms Pomalidomide-4'-C3-amine HCl CAS Number 2154342-45-5 Related CAS 2093388-20-4 (free base) Molecular Formula C16H19ClN4O4 Molecular Weight 366
including biomolecules containing azide groups through copper catalyzed azide-alkyne cycloaddition (CuAAC)
Product Name Azide-Hexanoyl-Val-Cit-PAB(m-PEG8)-MMAE Synonyms CAS Number Related CAS Molecular Formula C82H138N14O22 Molecular Weight 1672
P18h (AggFluor Halotag Ligand) Size:100nmol & SellmyerP18h is a HaloTag ligand incorporating the fluorogenic AggFluor P18 dye. AggFluor is derived from the synthetic GFP chromophore, 4 hydroxybenzylidene imidazolinone (HBI), and belongs to the class of molecular rotor fluorophores widely used in biological imaging due to their sensitivity to environmental factors such as viscosity. When bound to properly folded proteins, AggFluors are quenched and remain non fluorescent; however, protein misfolding or
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