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ispinesib cy3 resulting in decreased CDK12 substrate

SKU: 96345188859

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Description

resulting in decreased CDK12 substrate phosphorylation

83 SMILES Cl

Product Name Pomalidomide-C3-amine HCl Synonyms Pomalidomide-4'-C3-amine HCl CAS Number 2154342-45-5 Related CAS 2093388-20-4 (free base) Molecular Formula C16H19ClN4O4 Molecular Weight 366

Product Name Lenalidomide-PEG6-propargyl Synonyms Lenalidomide-4'-PEG6-propargyl CAS Number n/a Related CAS Molecular Formula C28H39N3O9 Molecular Weight 561

Product Name Pomalidomide-C4-acid Synonyms Pomalidomide-4'-C4-acid CAS Number 2225940-48-5 Related CAS Molecular Formula C18H19N3O6 Molecular Weight 373

ispinesib cy3 resulting in decreased CDK12 substrateIspinesib is an autophagic molecular degrader. It reduces mHTT levels through autophagic degradation by interacting with both the autophagosome protein microtubule associated protein 1A 1B light chain 3 (LC3)1 and mutant huntingtin protein (mHTT). It is also a potent, specific and reversible inhibitor of kinesin spindle protein (KSP) with Ki app of 1. 7 nM. Product Name ispinesib Synonyms 8F20, SB 715992 CAS Number 336113 53 2 Related CAS Molecular

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