Phthalimidinoglutarimide-5'-propargyl-C2-OH amine JTP-74057) is an orally active

JTP-74057) is an orally active MEK inhibitor that inhibits MEK1 and MEK2 with IC50s of about 2 nM

89 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCOCCOCCOCCOCCOCC#C)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

445 SMILES OCCCCCCNC(=O)COC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name Thalidomide-O-acetamido-C6-azide Synonyms Thalidomide-4'-O-acetamido-C6-azide CAS Number n/a Related CAS Molecular Formula C21H24N6O6 Molecular Weight 456

S)-AHPC-CO-C4-alkyne Synonyms CAS Number 2374122-28-6 Related CAS Molecular Formula C29H38N4O4S Molecular Weight 538

Phthalimidinoglutarimide-5'-propargyl-C2-OH amine JTP-74057) is an orally activeDegrader building block for targeted protein degradation. Contains an E3 ligase ligand with a linker and a function group, which can be conjugated to target protein ligands through straightforward chemical reactions. Product Name Phthalimidinoglutarimide 5' propargyl C2 OH Synonyms CAS Number 2229714 98 9 Related CAS Molecular Formula C18H18N2O4 Molecular Weight 326. 352 SMILES OCCCC#CC1=CC=C2C(CN(C3CCC(=O)NC3=O)C2=O)=C1 Purity (HPLC) >= 95% Shipping