(S,R,S)-AHPC-CO-PEG4-C2-Br Thalidomide Product Name Phthalimidinoglutarimide-C6-Br Synonyms Phthalimidinoglutarimide-4'-C6-Br

Product Name Phthalimidinoglutarimide-C6-Br Synonyms Phthalimidinoglutarimide-4'-C6-Br CAS Number n/a Related CAS Molecular Formula C19H23BrN2O3 Molecular Weight 407

Product Name Lenalidomide-acetamido-O-PEG1-C2-amine HCl Synonyms Lenalidomide-4'-acetamido-O-PEG1-C2-amine HCl CAS Number 1946779-34-5 Related CAS Molecular Formula C19H25ClN4O6 Molecular Weight 440

338 SMILES OC(=O)CCC(=O)NC1=CC=C2C(CN(C3CCC(=O)NC3=O)C2=O)=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

7 SMILES Cl

OC1=CC2=C(C=C1)C1(OC(=O)C3=CC=C(C=C13)C(=O)NCCOCCOCCOCCN=[N]#N)C1=CC=C(O)C=C1O2 Purity (HPLC): ≥ 95% Shipping Conditions: room temperature Storage Conditions: Refrigerated Regulatory Statement: For Research Use Only

(S,R,S)-AHPC-CO-PEG4-C2-Br Thalidomide Product Name Phthalimidinoglutarimide-C6-Br Synonyms Phthalimidinoglutarimide-4'-C6-BrDegrader building block for targeted protein degradation. Contains an E3 ligase ligand with a linker and a function group, which can be conjugated to target protein ligands through straightforward chemical reactions. Product Name (S,R,S) AHPC CO PEG4 C2 Br Synonyms CAS Number n a Related CAS Molecular Formula C33H49BrN4O8S Molecular Weight 741. 74 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCOCCOCCOCCOCCBr)C(C)(C)C)C=C1