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789 Purity (HPLC) >= 95% Solubility DMSO
Small molecule induced polymerization of BCL6 facilitates SIAH1 mediated degradation
Click reactions have several characteristics: the reaction between the detection moieties is efficient
The propargyl functional group is widely employed in click chemistry to undergo selective cycloaddition with azides
Product Name Mal-Acetyl-Beta-Ala-Val-Ala-PAB(m-PEG8) Synonyms CAS Number Related CAS Molecular Formula C42H66N6O16 Molecular Weight 911
Mal-Propionyl-PEG2-Val-Ala-PAB(m-PEG8)-MMAE mal-acetyl-dap-m-PEG4 789 Purity (HPLC) >= 95%SOLU KNEX cleavable linker features a Val Ala dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG2 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly
