Mal-Propionyl-Dap(m-PEG4)-Val-Ala-OH ptotac ligand Product Name DOTA-propargyl Synonyms CAS

Product Name DOTA-propargyl Synonyms CAS Number n/a Related CAS Molecular Formula C19H31N5O7 Molecular Weight 441

Product Name Mal-Propionyl-PEG8-Gly-Gly-Phe-Gly-PAB(m-PEG4)-MMAE Synonyms CAS Number Related CAS Molecular Formula C98H153N13O30 Molecular Weight 1993

With excitation maximum at 547 nm

such as the copper-catalyzed azide-alkyne cycloaddition (CuAAC) and the strain-promoted alkyne-azide cycloaddition (SPAAC)

31 SMILES FC(F)(F)C1=CC(SC2=C(Cl)C=CC=C2Cl)=C(C(=O)N2CC3=CC=CC(C#N)=C3C2)C(=O)N1 Purity (HPLC) >= 95% Physical Appearance White solid Solubility DMSO

Mal-Propionyl-Dap(m-PEG4)-Val-Ala-OH ptotac ligand Product Name DOTA-propargyl Synonyms CASSOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, a Mal Propionyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG, amine containing groups, or polysarcosine