DBCO-Hexanoyl-Val-Ala-PAB(m-PEG8)-Exatecan Size:1mg Product Name DOTA-PEG6-propargyl Synonyms CAS

Product Name DOTA-PEG6-propargyl Synonyms CAS Number n/a Related CAS Molecular Formula C31H55N5O13 Molecular Weight 705

419 SMILES OC(=O)CCCCCCNC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name Thalidomide-O-acetamido-PEG6-OH Synonyms Thalidomide-4'-O-acetamido-PEG6-OH CAS Number n/a Related CAS Molecular Formula C25H33N3O11 Molecular Weight 551

Product Name Thalidomide-5'-O-PEG2-C2-acid Synonyms CAS Number 2682112-08-7 Related CAS Molecular Formula C20H22N2O9 Molecular Weight 434

Product Name ispinesib Synonyms 8F20

DBCO-Hexanoyl-Val-Ala-PAB(m-PEG8)-Exatecan Size:1mg Product Name DOTA-PEG6-propargyl Synonyms CASSOLU KNEX cleavable linker features a Val Ala dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC