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Product Name Mal-Propionyl-Beta-Ala-Val-Ala-PAB(m-PEG8)-PNP Synonyms CAS Number Related CAS Molecular Formula C50H71N7O20 Molecular Weight 1090
HQ461 is a molecular glue that promotes CDK12-DDB1 interaction to trigger cyclin K degradation
Product Name Lenalidomide-acetamido-O-PEG1-OH Synonyms Lenalidomide-4'-acetamido-O-PEG1-OH CAS Number n/a Related CAS Molecular Formula C17H19N3O6 Molecular Weight 361
6-SiR-CA CAS Number Related CAS Molecular Formula C37H48ClN3O5Si Molecular Weight 678
Product Name CA-SiR Synonyms SiR-Halo
Mal-Acetyl-Dap(m-PEG4)-Val-Ala-PAB(m-PEG8)-Exatecan Biotin Product Name Mal-Propionyl-Beta-Ala-Val-Ala-PAB(m-PEG8)-PNP Synonyms CASSOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, a Mal Acetyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Acetyl group may also improve retro Michael addition stability during antibody conjugation. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload is Exatecan,
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