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Fmoc-Val-Cit-PAB amine-amine 064 SMILES [H]C(=O)C1=CC=C(Br)C(OC([2H])([2H])[2H])=C1 Purity (HPLC)

SKU: 79921354479

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Description

064 SMILES [H]C(=O)C1=CC=C(Br)C(OC([2H])([2H])[2H])=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name Mal-Acetyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG8)-Exatecan Synonyms CAS Number Related CAS Molecular Formula C80H111FN12O27 Molecular Weight 1691

The photostability and brightness of CPY make it a valuable tool for detailed imaging of cellular dynamics

96 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCCOCCOCCOCCOCCOCCOCC(O)=O)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Contains an E3 ligase ligand with alkyl linker and a terminal piperazine moiety

Fmoc-Val-Cit-PAB amine-amine 064 SMILES [H]C(=O)C1=CC=C(Br)C(OC([2H])([2H])[2H])=C1 Purity (HPLC)Fmoc Val Cit PAB is a cleavable ADC linker featuring a ValCit dipeptide and a para aminobenzyl (PAB) spacer. The ValCit sequence is selectively cleaved by cathepsin B in lysosomes, while the para aminobenzyl (PAB) spacer supports self immolative release of the attached drug, and the Fmoc protecting group can be removed to enable further functionalization or conjugation. Product Name Fmoc Val Cit PAB Synonyms Fmoc VC PAB OH CAS Number 159858 22 7

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