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137 Purity (HPLC) >= 95% Solubility DMSO
293 Purity (HPLC) >= 95% Solubility DMSO
29 SMILES O=C1CCC(N2C=C(N=N2)C2=CSC=C2)C(=O)N1 Purity (HPLC) >= 95% Physical Appearance White solid Solubility DMSO
85 Purity (HPLC) >= 95% Physical Appearance Off White Solid Optical Properties Abs/Em Maxima: n/a Solubility DMSO
NCCOCCOCCOCCOCCOCCNC(=O)COC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only
Mal-Propionyl-Beta-Ala-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan biotin 137 Purity (HPLC) >= 95%SOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker
