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83 SMILES Cl
Product Name Lenalidomide-5'-CO-C5-amine HCl Synonyms CAS Number n/a Related CAS Molecular Formula C19H25ClN4O4 Molecular Weight 408
Product Name Azide-Dap(m-PEG4)-Val-Ala-PAB(m-PEG8)-MMAE Synonyms CAS Number Related CAS Molecular Formula C86H145N13O26 Molecular Weight 1777
Structural basis for the action of the drug trametinib at KSR-bound MEK
Product Name DBCO-Lys(m-PEG4)-Val-Ala-PAB(m-PEG4) Synonyms CAS Number Related CAS Molecular Formula C60H85N7O16 Molecular Weight 1160
Mal-Propionyl-PEG8-Gly-Gly-Phe-Gly-PAB(m-PEG4)-MMAE Size:1mg 83 SMILES ClSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG8 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a
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