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Product Name Mal-Propionyl-PEG4-Val-Ala-PAB(m-PEG4)-PNP Synonyms CAS Number Related CAS Molecular Formula C50H71N7O20 Molecular Weight 1090
Product Name Pomalidomide-CO-C4-Br Synonyms Pomalidomide-4'-CO-C4-Br CAS Number 2162120-76-3 Related CAS Molecular Formula C18H18BrN3O5 Molecular Weight 436
Product Name Mal-Propionyl-PEG6-Gly-Gly-Phe-Gly-PAB(m-PEG4)-PNP Synonyms CAS Number Related CAS Molecular Formula C61H84N10O23 Molecular Weight 1325
Iberdomide (CC-220) is an orally active and potent cereblon (CRBN) E3 ligase modulator (CELMoD) with an IC50 of 150
such as MRI contrast agents
MC-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE fluorescent Product Name Mal-Propionyl-PEG4-Val-Ala-PAB(m-PEG4)-PNP Synonyms CASSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers
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