HiXCap™ E1 Cap Analogs [5] Gruenke

[5] Gruenke

Wobble base-pairing of dI makes it particularly valuable in the design of degenerate PCR or sequencing primers

Oxidation: 3 minute coupling time (inosine is susceptible to damage by iodine)

and a 2'-O-methoxyethyl (MOE) modification

"MicroRNA detection by northern blotting using locked nucleic acid probes

HiXCap™ E1 Cap Analogs [5] GruenkeHiXCap E1 is a chemically modified cap analogue that is incorporated into mRNA through co transcription to ensure that the 5' end of the mRNA forms the correct cap structure, which is a necessary condition for ribosome recognition and translation initiation. Its molecular formula is m7G(5')pppA(2'O Et)pG. Download HiXCap Brochure for more technical details. Applications Significantly enhance the translation efficiency of mRNA. It can resist