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Mal-Lys(m-PEG4)-Val-Ala-PAB(m-PEG4)-MMAE acid Product Name Pomalidomide-CO-C1-bromide Synonyms Pomalidomide-4'-CO-C1-bromide

SKU: 5446417206

4.6
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Description

Product Name Pomalidomide-CO-C1-bromide Synonyms Pomalidomide-4'-CO-C1-bromide CAS Number 2351106-38-0 Related CAS Molecular Formula C15H12BrN3O5 Molecular Weight 394

Azide has been extensively used in click chemistry

Product Name Pomalidomide-CO-C5-azide Synonyms Pomalidomide-4'-CO-C5-azide CAS Number 2227423-33-6 Related CAS Molecular Formula C19H20N6O5 Molecular Weight 412

Product Name Thalidomide-5'-O-PEG2-C2-acid Synonyms CAS Number 2682112-08-7 Related CAS Molecular Formula C20H22N2O9 Molecular Weight 434

722 SMILES: [O-]C(=O)C1=CC=C(C=C1C1=C2C=C3CCC[N+]4=C3C(CCC4)=C2OC2=C3CCCN4CCCC(C=C12)=C34)C(=O)NCCCN=[N]#N Purity (HPLC): ≥ 95% Shipping Conditions: room temperature Storage Conditions: Refrigerated Regulatory Statement: For Research Use Only

Mal-Lys(m-PEG4)-Val-Ala-PAB(m-PEG4)-MMAE acid Product Name Pomalidomide-CO-C1-bromide Synonyms Pomalidomide-4'-CO-C1-bromideSOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, a Mal Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to

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