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Fmoc-Val-Cit-PAB-PNP Size:100mg BI-3802 is a highly potent

SKU: 50348850561

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Description

BI-3802 is a highly potent BCL6 degrader and inhibits the Bric-a-brac (BTB) domain of BCL6 with an IC50 of

293 Purity (HPLC) >= 95% Solubility DMSO

Product Name DOTA-tris(t-Bu)ester-C3-alcohol Synonyms CAS Number n/a Related CAS Molecular Formula C31H59N5O8 Molecular Weight 629

Product Name BG-PhN3 Synonyms SNAP-PhN3 CAS Number Related CAS Molecular Formula C20H17N9O2 Molecular Weight 415

AggFluor P1 exhibits fluorescence in both misfolded oligomers and insoluble aggregates but cannot differentiate between these species

Fmoc-Val-Cit-PAB-PNP Size:100mg BI-3802 is a highly potentFmoc Val Cit PAB PNP is a cleavable ADC linker used in antibodydrug conjugate (ADC) development, designed to enable enzyme responsive payload release in tumor targeted applications. The ValCit dipeptide is optimized for cathepsin B cleavage in lysosomal environments, while the para aminobenzyl (PAB) spacer supports self immolative release of the attached drug. The p nitrophenyl (PNP) group functions as an efficient leaving group for conjugation to

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