Mal-Lys(m-PEG4)-Val-Cit-PAB(m-PEG4)-Exatecan Size:25mg S)-AHPC-CO-PEG6-OH Synonyms CAS Number n/a

S)-AHPC-CO-PEG6-OH Synonyms CAS Number n/a Related CAS Molecular Formula C35H54N4O10S Molecular Weight 722

392 Purity (HPLC) >= 95% Solubility DMSO

Indisulam promotes the recruitment of RBM39 (RNA binding motif protein 39) to the CUL4-DCAF15 E3 ubiquitin ligase

Product Name BG-DOTA-tris(t-Bu) Synonyms SNAP-DOTA-tris(t-Bu) CAS Number n/a Related CAS Molecular Formula C41H64N10O8 Molecular Weight 825

- CAS Number: 2307477-23-0 Molecular Formula: C18H22ClN3O5 Molecular Weight: 395

Mal-Lys(m-PEG4)-Val-Cit-PAB(m-PEG4)-Exatecan Size:25mg S)-AHPC-CO-PEG6-OH Synonyms CAS Number n/aSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by