Propargyl-Acetyl-Val-Ala-PAB(m-PEG8)-MMAE Size:10mg This enables researchers to visualize

This enables researchers to visualize and track proteins or other cellular structures with minimal background interference

Product Name Mal-Propionyl-Dap(m-PEG4)-Val-Ala-PAB(m-PEG4)-PNP Synonyms CAS Number Related CAS Molecular Formula C52H74N8O21 Molecular Weight 1147

Nat Chem Biol 2020

Chloroquinaxoline sulfonamide (CQS) promotes the recruitment of RBM39 (RNA binding motif protein 39) to the CUL4-DCAF15 E3 ubiquitin ligase for degadation

CA-SS-BODIPY is a cleavable HaloTag ligand featuring a disulfide bond that can be cleaved using a reducing agent

Propargyl-Acetyl-Val-Ala-PAB(m-PEG8)-MMAE Size:10mg This enables researchers to visualizeSOLU KNEX cleavable linker features a Val Ala dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing