(S,R,S)-AHPC-acetamido-O-PEG1-C2-Cl 5' NCC(=O)NC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95%

NCC(=O)NC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

66 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCCOCCOCCBr)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

OC1=CC2=C(C=C1)C1(OC(=O)C3=CC=C(C=C13)C(=O)NCCOCCOCCOCCN=[N]#N)C1=CC=C(O)C=C1O2 Purity (HPLC): ≥ 95% Shipping Conditions: room temperature Storage Conditions: Refrigerated Regulatory Statement: For Research Use Only

Product Name 4-[di(methyl-d3)amino]benzonitrile Synonyms CAS Number 88889-02-5 Related CAS Molecular Formula C9H10N2 Molecular Weight 152

Product Name tert-butyl N-[(4-bromophenyl)methyl]-N-(methyl-d3)carbamate Synonyms tert-butyl N-[(4-bromophenyl)methyl]-N-(²H3)methylcarbamate CAS Number n/a Related CAS Molecular Formula C13H18BrNO2 Molecular Weight 303

(S,R,S)-AHPC-acetamido-O-PEG1-C2-Cl 5' NCC(=O)NC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95%Degrader building block for targeted protein degradation. Contains an E3 ligase ligand with a linker and a function group, which can be conjugated to target protein ligands through straightforward chemical reactions. Product Name (S,R,S) AHPC acetamido O PEG1 C2 Cl Synonyms CAS Number n a Related CAS Molecular Formula C28H39ClN4O6S Molecular Weight 595. 15 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCCOCCCl)C(C)(C)C)C=C1