Mal-Propionyl-PEG8-Gly-Gly-Phe-Gly-PAB(m-PEG4) deuterium-labeled-amine S)-AHPC-acetamido-O-PEG5-C1-acid Synonyms CAS Number 2361117-11-3

S)-AHPC-acetamido-O-PEG5-C1-acid Synonyms CAS Number 2361117-11-3 Related CAS Molecular Formula C36H54N4O12S Molecular Weight 766

85 SMILES: Cl

367 SMILES OCCCCCC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

SHP099 is a highly potent (IC50 = 0

037 Purity (HPLC) >= 95% Solubility DMSO

Mal-Propionyl-PEG8-Gly-Gly-Phe-Gly-PAB(m-PEG4) deuterium-labeled-amine S)-AHPC-acetamido-O-PEG5-C1-acid Synonyms CAS Number 2361117-11-3SOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG8 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. Derived from established ADC linker