Mal-Lys(m-PEG4)-Val-Cit-PAB(m-PEG4)-MMAE mal-propionyl-dap-m-PEG4 S)-AHPC-CO-PEG3-C2-acid Synonyms CAS Number 2140807-42-5

S)-AHPC-CO-PEG3-C2-acid Synonyms CAS Number 2140807-42-5 Related CAS Molecular Formula C32H46N4O9S Molecular Weight 662

392 Purity (HPLC) >= 95% Solubility DMSO

Wolstenholme

HaloTag is a self-labeling protein derived from the haloalkane dehalogenase DhaA from Rhodococcus rhodochrous

a synthetic antibiotic

Mal-Lys(m-PEG4)-Val-Cit-PAB(m-PEG4)-MMAE mal-propionyl-dap-m-PEG4 S)-AHPC-CO-PEG3-C2-acid Synonyms CAS Number 2140807-42-5SOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to