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Product Name Thalidomide-O-PEG1-C2-Br Synonyms Thalidomide-4'-O-PEG1-C2-Br CAS Number n/a Related CAS Molecular Formula C17H17BrN2O6 Molecular Weight 425
Product Name Mal-Propionyl-PEG8-Val-Ala-PAB(m-PEG4)-PNP Synonyms CAS Number Related CAS Molecular Formula C58H89N7O23 Molecular Weight 1252
eLife 2020
& Hellerschmied
NCCOCCOCCOCCOCCOCCOCCC(=O)NC1=CC=C2C(=O)N(CC2=C1)C1CCC(=O)NC1=O Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only
Mal-Propionyl-Beta-Ala-Val-Ala-PAB(m-PEG8)-MMAE Size:5mg Product Name Thalidomide-O-PEG1-C2-Br Synonyms Thalidomide-4'-O-PEG1-C2-BrSOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate
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