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Product Name Azide-Lys(m-PEG4)-Val-Ala-PAB(m-PEG4) Synonyms CAS Number Related CAS Molecular Formula C41H70N8O14 Molecular Weight 899
The payload is monomethyl auristatin E (MMAE)
Product Name Lenalidomide-PEG4-C2-azide Synonyms Lenalidomide-4'-PEG4-C2-azide CAS Number 2399455-55-9 Related CAS Molecular Formula C23H32N6O7 Molecular Weight 504
Bioconjugate Chemistry
Product Name Mal-Propionyl-PEG4-Val-Cit-PAB(m-PEG4)-Exatecan Synonyms CAS Number Related CAS Molecular Formula C71H94FN11O22 Molecular Weight 1472
Mal-Propionyl-PEG6-Val-Cit-PAB(m-PEG4)-Exatecan Size:10mg Product Name Azide-Lys(m-PEG4)-Val-Ala-PAB(m-PEG4) Synonyms CASSOLU KNEX cleavable linker features a Val Cit dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG6 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I
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