Propargyl-Gly(m-PEG4)-Val-Cit-PAB-PNP heterocycle Product Name Pomalidomide-C4-amine HCl Synonyms

Product Name Pomalidomide-C4-amine HCl Synonyms Pomalidomide-4'-C4-amine HCl CAS Number 2162120-73-0 Related CAS 1957236-34-8 (free base) Molecular Formula C17H21ClN4O4 Molecular Weight 380

NCCOCCOCC(=O)NC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

enables reversible and dose-dependent inhibition of CAR activity by recruiting the proteasome

Biochemistry

486 SMILES: NCCCCCNC(=O)C1=CC=C2C(=C1)C(=O)OC21C2=CC=C(O)C=C2OC2=C1C=CC(O)=C2 Purity (HPLC): ≥ 95% Shipping Conditions: room temperature Storage Conditions: Refrigerated Regulatory Statement: For Research Use Only

Propargyl-Gly(m-PEG4)-Val-Cit-PAB-PNP heterocycle Product Name Pomalidomide-C4-amine HCl SynonymsSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Propargyl Gly(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The propargyl functional group is widely employed in click chemistry to undergo selective cycloaddition with azides. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG, amine containing groups, or