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DBCO-Dap(m-PEG4)-Val-Cit-PAB(m-PEG8) Size:100mg CP-CPY is a SNAP-tag substrate

SKU: 23155889744

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Description

CP-CPY is a SNAP-tag substrate containg CPY dye

The inhibiting SHP2 activity of SHP099 is through an allosteric mechanism

The strain in DBCO’s cyclooctyne ring drives the reaction forward by releasing energy when it transitions to the triazole product

Product Name Thalidomide-C4-OH Synonyms Thalidomide-4'-C4-OH CAS Number n/a Related CAS Molecular Formula C17H18N2O5 Molecular Weight 330

Click chemistry describes a class of chemical reactions that use bio-orthogonal or biologically unique moities to label and detect a molecule of interest using a two-step procedure

DBCO-Dap(m-PEG4)-Val-Cit-PAB(m-PEG8) Size:100mg CP-CPY is a SNAP-tag substrateSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a DBCO Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further

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