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Mal-Propionyl-PEG6-Gly-Gly-Phe-Gly-PAB(m-PEG4) mmae 054 SMILES [2H]C([2H])([2H])OC1=CC=C(Br)C=C1 Purity (HPLC)

SKU: 12914069975

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Description

054 SMILES [2H]C([2H])([2H])OC1=CC=C(Br)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

specific and reversible inhibitor of kinesin spindle protein (KSP) with Ki app of 1

5(6)-FAM PEG3 azide is an excellent alkyne-reactive fluorescent reagent for labeling alkyne-containing biological molecules through click chemistry

which readily reacts with an alkyne via click chemistry

Bioconjugate Chemistry

Mal-Propionyl-PEG6-Gly-Gly-Phe-Gly-PAB(m-PEG4) mmae 054 SMILES [2H]C([2H])([2H])OC1=CC=C(Br)C=C1 Purity (HPLC)SOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG6 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. Derived from established ADC linker

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