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Mal-Propionyl-PEG8-Val-Cit-PAB(m-PEG4) Size:50mg P18h is a HaloTag ligand

SKU: 10870035511

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Description

P18h is a HaloTag ligand incorporating the fluorogenic AggFluor P18 dye

This probe is also efficiently excited by the 543 nm spectral line of the Ar - Kr mixed gas laser commonly used in many confocal laser-scanning microscopes

Product Name Thalidomide-O-PEG1-propargyl Synonyms Thalidomide-4'-O-PEG1-propargyl CAS Number 2098487-79-5 Related CAS Molecular Formula C18H16N2O6 Molecular Weight 356

SHP099 is a highly potent (IC50 = 0

362 SMILES CC(C)(C)OC(=O)CCOCCN1CCNCC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Mal-Propionyl-PEG8-Val-Cit-PAB(m-PEG4) Size:50mg P18h is a HaloTag ligandSOLU KNEX cleavable linker features a Val Cit dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG8 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. Derived from established ADC linker architectures, SOLU KNEX

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