Desynchronization An instant speed board wipe is always welcome, even one as limited as Desynchronization, which could actually whiff in an EDH game with the proliferating number of legendary creatures out there
It also doesn't change day into night, so your daybound Werewolves stay Human
Red also emphasizes haste creatures, allowing them to attack as soon as they hit the battlefield
Counter Blitz is all about +1/+1 counterscreating them, proliferating them, and moving them around your board
If this were any other colour pairing but blue green I suspect it would be the most played of all the 3 mana hard counters in the cube but Simic is an uncommon counter based control option as it is so useless at dealing with creatures
This is thanks to it being completely free to cast, as long as its the first spell you cast